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First received: December 06, 2024

Clinical Trial: Therapeutic Effect of Manuka Honey Oral Rinse on Fibroblast Growth Factor-21 in Periodontitis Patients Undergoing Hemodialysis

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Periodontitis

Study Type: INTERVENTIONAL


Official Title: Therapeutic Effect of Manuka Honey Oral Rinse on Fibroblast Growth Factor-21 in Periodontitis Patients Undergoing Hemodialysis

Brief Summary: Chronic Kidney Disease (CKD) has a strong association with chronic periodontitis, an oral disease causing tooth loss linked to inflammation and malnutrition.While periodontitis affects 12.7% of the general population, its prevalence can rise to 39% in certain racial groups, and a dose-response relationship exists with CKD.End Stage Renal Disease (ESRD) patients show a prevalence of periodontitis ranging from 29% to 85.6%.Uremia, immunosuppression, and vitamin D deficiency are suggested factors in the etiology of…

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