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Accelerated response and reduced chemotherapy with ruxolitinib-based regimen therapy in pediatric hemophagocytic lymphohistiocytosis: a retrospective comparison with HLH-94 regimen

Abstract: To compare the efficacy of a Ruxolitinib-based regimen versus the conventional HLH-94 protocol in children with newly diagnosed hemophagocytic lymphohistiocytosis (HLH).…

Date: 2026-03-26

Value, development challenges, and strategies for gaining internal endorsement of digitally connected subcutaneous drug delivery devices: a survey of pharmaceutical stakeholders

Abstract: Connected drug delivery devices such as combination products that integrate traditional drug delivery systems with digital connectivity features represent an opportunity…

Date: 2026-03-26

Life Story Work as an inclusive methodology to explore identity in intellectual disability

Abstract: This study explores how young people with intellectual disability (ID) construct and negotiate their identities through life stories, adopting a narrative perspective…

Date: 2026-03-26

Development and validation of a risk prediction model of delayed onset of lactogenesis among mothers with gestational diabetes mellitus: a prospective multicenter study

Abstract: The aim of this study is to develop and validate a prediction model of delayed onset of lactogenesis among mothers with gestational diabetes mellitus. This was a…

Date: 2026-03-26

The development and validation of a machine learning algorithm for identifying lateral lymph nodes skip metastasis in papillary thyroid cancer

Abstract: Skip metastasis from papillary thyroid cancer (PTC) is often unpredictable and characterized by lateral lymph node metastasis without central lymph node metastasis. Our…

Date: 2026-03-26

From adolescence to adulthood: validation of the levels of personality functioning questionnaire in a Turkish adult sample

Abstract: The Levels of Personality Functioning Questionnaire (LoPF-Q) is a self-report tool developed to assess impairments in personality functioning, informed by Criterion A of…

Date: 2026-03-26

Multicenter machine learning study for long-term prediction of acute kidney injury after complete mesocolic excision: integrating inflammatory biomarkers and transfusion-related risk factors

Abstract: Complete mesocolic excision (CME) is a technically complex and highly invasive surgical approach, and patients undergoing CME are consequently at elevated risk of…

Date: 2026-03-26

Radiomics-machine learning model for predicting invasiveness of subcentimeter subsolid lung adenocarcinoma: a validation study with external cohort and SHAP interpretability

Abstract: Preoperative discrimination of invasive adenocarcinoma (IAC) from pre-invasive lesions in subcentimeter subsolid nodules (SSNs) remains challenging using conventional…

Date: 2026-03-26

Integrated ultrasound-based radiomics and deep learning models in screening breast intraductal high-risk lesions or carcinoma: a multicenter retrospective study

Abstract: The aim of this study was to explore the diagnostic performance of ultrasound (US)-based radiomics combined with deep learning (DL) in the screening of high-risk and…

Date: 2026-03-26

Children’s insights into nutritional culture and habits in Abu Dhabi

Abstract: The United Arab Emirates (UAE) has identified childhood obesity as a significant public health concern. Designing targeted interventions to promote healthy eating habits…

Date: 2026-03-26