why choose us

First received: January 26, 2025

Clinical Trial: Comparison of Standard Versus High Dose Urokinase for Dysfunctional Tunneled Dialysis Catheters in Haemodialysis Patients: a Randomized Controlled Trial

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Hemodialysis

Study Type: INTERVENTIONAL


Official Title: Comparison of Standard Versus High Dose Urokinase for Dysfunctional Tunneled Dialysis Catheters in Haemodialysis Patients: a Randomized Controlled Trial

Brief Summary: Tunneled dialysis catheters (TDCs) remain a frequent form of vascular access for patients undergoing long-term haemodialysis (HD).In our local setting, thrombolytic therapy with urokinase is used as first line therapy to restore catheter patency in patients who develop TDC dysfunction before considering a TDC exchange which is more invasive, requires hospital admission, and involves a higher cost.There are no published local data on the efficacy of Urokinase, though this is widely used in local practice as first…

Read more