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First received: February 14, 2025

Clinical Trial: A Study to Learn if Study Medicines Called Cyclosporine and Clarithromycin Affect How the Body Processes the Other Study Medicine Called PF-07328948 in Healthy Adults

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Healthy Adults

Study Type: INTERVENTIONAL


Official Title: A Phase 1, Open-Label, Fixed-Sequence Study to Evaluate the Effect of OATP Inhibition on the Single Dose Pharmacokinetics of PF-07328948 in Healthy Adult Participants.

Brief Summary: The purpose of this study is to learn about the effect of cyclosporine, an immunosuppressant (medicine that suppresses the immune system), on the pharmacokinetics (PK) of PF-07328948 in healthy participants (Part A).The study may also estimate the effect of clarithromycin, an antibiotic, on the PK of PF-07328948 in healthy participants (Part B is optional).This study is seeking participants who:are 18 years of age or olderare male or female who are not of childbearing potentialare healthy (do not have a disease)…

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