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First received: January 24, 2026

Clinical Trial: 3°C Saline Injection at the Duodenal Papilla to Prevent Post-ERCP Pancreatitis

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Pancreatitis

Study Type: INTERVENTIONAL


Official Title: Effect of 3°C Saline Irrigation Toward the Duodenal Papilla to Prevent Post-ERCP Pancreatitis: Protocol for a Multicenter, Controlled, Randomized, Patient-Blinded Trial in Bogotá, Colombia.

Brief Summary: Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic procedure used to diagnose and treat problems in the bile ducts and pancreas.One of its most common complications is **post-ERCP pancreatitis**.This multicenter randomized clinical trial will evaluate whether **cooling the duodenal papilla** with **sterile saline at 3°C** immediately after ERCP can reduce the risk of post-ERCP pancreatitis compared with standard ERCP care.Adults **?18 years** with a **native papilla** scheduled for diagnostic…

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