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First received: September 18, 2025

Clinical Trial: Sarcopenia and CRP-TyG Index (CTI) as Predictors of Immunotherapy Response in Metastatic Non-Small Cell Lung Cancer

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Metastatic Non-small Cell Lung Cancer

Study Type: OBSERVATIONAL


Official Title: The Impact of Sarcopenia and CRP-TyG Index (CTI) on Immunotherapy Response in Patients With Metastatic Non-Small Cell Lung Cancer: A Single-Center Retrospective Analysis

Brief Summary: This study investigates the impact of sarcopenia and the CRP-TyG Index (CTI) on immunotherapy outcomes in patients with metastatic non-small cell lung cancer (NSCLC).Medical records of 115 adult patients treated with immune checkpoint inhibitors at Ankara Etlik City Hospital between November 2022 and December 2024 will be retrospectively analyzed.Sarcopenia will be determined from CT-based skeletal muscle index (SMI) measurements at the L3 vertebral level.SMI will be calculated as skeletal muscle area (cm²)…

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