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First received: May 20, 2026

Clinical Trial: Atropine Alone vs Atropine Plus Bifocal Spectacles for Myopia Control in Children

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Myopia
Progressive Myopia
Refractive Errors

Study Type: INTERVENTIONAL


Official Title: Investigating Comparative Efficacy of Myopia Control Strategies and Genetic Underpinnings: A Randomized Controlled Trial

Brief Summary: Background: Myopia (nearsightedness) is a growing global health concern, projected to affect 50% of the world population by 2050. Children with progressive myopia are at risk of serious ocular complications including myopic maculopathy, glaucoma, and retinal detachment. Low-dose atropine (0.05%) has shown efficacy in slowing myopia progression, and optical interventions such as bifocal spectacles may provide additional benefits by altering peripheral retinal defocus. Objective: This randomized controlled trial…

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