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Course: Female Patient Presenting With Increasing Pedal Edema

CME Credits: 1.00

Released: 2023-12-06

A female patient in their 20s presented with increasing pedal edema. The patient’s medical history included a heart transplant. On examination, their jugular venous pulse was elevated with marked V waves. Transthoracic echocardiography demonstrated severe tricuspid regurgitation (TR) with a severely dilated right ventricle (RV) and right atrium with preserved left ventricle systolic function. Transesophageal echocardiography was performed to determine suitability for transcatheter therapies for her severe TR (Figure, Video). Imaging revealed a congenital bicuspid-tricuspid valve with a large anterior and posterior leaflet with medial and lateral commissures and no discernable septal leaflet. The etiology of the patient’s TR is due to leaflet malcoaptation from a dilated RV. Bicuspid-tricuspid valves are exceedingly rare, composing less than 5% of previously documented tricuspid valve subtypes.1,2 The natural progression of congenital bicuspid-tricuspid valves is unknown. To the authors’ knowledge, bicuspid-tricuspid valve resulting in severe TR in a heart transplant recipient has not been previously reported.


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