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Research Article: Comparative Analysis of Hematological and Biochemical Changes in Neonates among Women with and without COVID-19 Infection during Pregnancy

Date Published: 2023-08-10

Abstract:
The aim of this study is to evaluate the test results of neonates delivered by COVID-19-positive mothers during pregnancy with those of neonates born to unvaccinated mothers who are COVID-19-free. A cohort study was conducted on 367 pregnant women who gave birth at Premiere Hospital, Timisoara, Romania, between May 2021 and February 2022. Two groups were established: Group 1, with 167 pregnant women infected with COVID-19, and Group 2, with 200 pregnant women who were not affected by COVID-19 during pregnancy. Maternal laboratory examination did not exhibit significant variations except for platelet count. In neonatal blood tests, WBC had a significantly lower median value in the group born to COVID-19-free mothers. Neonatal anemia and leukocytosis showed slightly higher prevalence in Group 1, but the differences were not statistically significant. This study suggests that maternal COVID-19 infection during pregnancy does not have significant associations with most maternal and neonatal characteristics.

Introduction:
The COVID-19 (Appendix A) pandemic has exerted a profound impact on global health, exerting its influence upon individuals spanning diverse age groups and populations [1,2]. Of particular concern was the potential transmission of SARS-CoV-2 from infected women during pregnancy to their developing fetuses [3,4]. According to current data, maternal infection with COVID-19 during pregnancy could have consequences for the outcome of newborns. Recent investigations have revealed an increased risk of adverse newborn…

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