Research Article: Impact of Access Site on Periprocedural Bleeding and Cerebral and Coronary Events in High-Bleeding-Risk Percutaneous Coronary Intervention: Findings from the RIVA-PCI Trial
Abstract:
The preference for using transradial access (TRA) over transfemoral access (TFA) in patients requiring percutaneous coronary intervention (PCI) is based on evidence suggesting that TRA is associated with less bleeding and fewer vascular complications, shorter hospital stays, improved quality of life, and a potential beneficial effect on mortality. We have limited study data comparing the two access routes in a patient population with atrial fibrillation (AF) undergoing PCI, who have a particular increased risk of bleeding, while AF itself is associated with an increased risk of thromboembolism.
Introduction:
Coronary artery disease (CAD) is a major contributor to illness and death worldwide. Patients with CAD and non-valvular atrial fibrillation (AF) who are treated with percutaneous coronary intervention (PCI) require oral anticoagulant (OAC) and additional antiplatelet therapy to prevent thromboembolic events and are therefore exposed to a bleeding risk [1], while AF itself is associated with an increased thromboembolic risk.
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