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Research Article: An efficacy and safety evaluation of montelukast + fluticasone propionate vs. fluticasone propionate in the treatment of cough variant asthma in children: a meta-analysis

Date Published: 2023-12-05

Abstract:
This study aimed to evaluate the efficacy and safety of montelukast (Mon) + fluticasone propionate (Flu) versus Flu in the treatment of cough variant asthma (CVA) in children.

Introduction:
Cough variant asthma (CVA), a phenotype of asthma that exhibits predominantly or solely airway hyperresponsiveness and cough but without wheezing or dyspnea [1, 2], is the most common cause of chronic cough [3]. Patients with CVA tend to experience hidden onsets, long courses, and repeated illnesses that directly affect their study, life, work, and sleep, and heavily affect their economic and mental well-being [4]. Induction therapy consisting of beta2-agonists, leukotriene receptor antagonists, and inhaled…

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