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Research Article: Associations of medicine use and ejection fraction with the coexistence of frailty and sarcopenia in a sample of heart failure outpatients: a cross-sectional study

Date Published: 2023-12-05

Abstract:
Frailty and sarcopenia have been extensively studied in heart failure (HF) patients, but their coexistence is unknown. The aim of this work is to describe the coexistence of these conditions in a sample of HF outpatients and its association with the use of medication and left-ventricular ejection fraction.

Introduction:
The syndrome of heart failure (HF) is a global public health problem in rapid expansion in both developed and developing countries [1]. As a condition associated with systemic multisystem dysfunction, HF is often accompanied by various comorbidities, which contribute to worst outcomes [2] and a heavier burden on health systems [3]. Two frequent comorbidities associated with HF are frailty and sarcopenia, with an overall estimated prevalence of 44.5% and 34.0% in elderly HF patients, respectively [4, 5]. Both…

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