Research Article: Experience of Daily Life with Generalized Myasthenia Gravis: A Qualitative Investigation and Assessment of Instrument Content Validity
Abstract:
Generalized myasthenia gravis (gMG) is a rare autoimmune disease. Symptoms of gMG are diverse, and understanding of their impact on patients is limited. This qualitative study aimed to provide an in-depth exploration of patients’ daily experiences of gMG.
Introduction:
Generalized myasthenia gravis (gMG) is a rare, chronic, autoimmune disease of the neuromuscular junction, affecting 14–20 out of every 100,000 people in the USA, with a worldwide prevalence of approximately 200 per 1 million people [1]. Clinically, gMG is characterized by fluctuating muscle weakness, fatiguability with mild physical activity/as the day progresses, and in severe cases hospitalization [1]. Symptoms are due primarily to the production of antibodies that bind the acetylcholine receptor, resulting in…
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