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Research Article: Clinical Outcomes in Patients with Rheumatoid Arthritis After Switching Between Interleukin-6-Receptor Inhibitors and Janus Kinase Inhibitors: Findings from an Observational Study

Date Published: 2023-10-31

Abstract:
This observational study evaluated response in patients with rheumatoid arthritis (RA) who switched from an interleukin-6 receptor inhibitor (IL-6Ri) to a Janus kinase inhibitor (JAKi) and vice versa.

Introduction:
Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease, characterized by synovial inflammation in multiple joints, leading to progressive and irreversible joint damage. If appropriate treatment is not provided, RA can cause significant pain and swelling in the hands and feet, loss of physical function, and a deterioration in the overall quality of life [1, 2].

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