Research Article: COMPASS: deCOMPressing stomA and two-Stage elective resection vs. emergency reSection in patients with left-sided obstructive colon cancer
Abstract:
Colorectal cancer stands as a prevalent cause of cancer-related mortality, necessitating effective treatment strategies. Acute colonic obstruction occurs in approximately 20% of patients and represents a surgical emergency with substantial morbidity and mortality. The optimal approach for managing left-sided colon cancer with acute colonic obstruction remains debatable, with no consensus on whether emergency resection or bridge-to-surgery, involving initial decompressing stoma and subsequent elective resection after recovery, should be employed. Current studies show a decrease in morbidity and short-term mortality for the bridge-to-surgery approach, yet it remains unclear if the long-term oncological outcome is equivalent to emergency resection.
Introduction:
Colorectal cancer is the third leading cause of cancer death in both men and women in the USA [1] and the second leading cause of cancer death in men and the third leading cause of cancer death in women in Europe [2]. Worldwide, colorectal cancer accounts for 19.0 million (18.5–19.5) disability-adjusted life years (DALYs) [3]. The risk of developing colorectal cancer increases with age. More than half of patients develop the disease after the age of 70; only about 10% of cancers occur before the age of 55.…
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