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Research Article: Conditional diagnostic accuracy according to inflammation status and age for diagnosing tuberculous effusion

Date Published: 2023-11-23

Abstract:
Tuberculous effusion varies from lymphocyte-dominant to neutrophilic effusion according to inflammation status. The criteria of adenosine deaminase (ADA) and lymphocyte/neutrophil (L/N) ratio have yet not been evaluated across different disease conditions.

Introduction:
Tuberculous pleural effusion is the chronic accumulation of inflammatory fluid in the pleural space caused by the Mycobacterium tuberculosis infection of the pleura [1]. A definitive diagnosis is difficult because of the low sensitivity of bacterial culture methods (<?10%: acid-fast bacilli of pleural fluid, 20–30%: M. tuberculosis culture of the fluid) [2]. In obscure cases, closed needle pleural biopsy is conducted; however, this invasive method yields only a confirmation of 60–80% for tuberculosis pleurisy…

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