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Research Article: A cross-sectional survey of potential factors, motivations, and barriers influencing research participation and retention among people who use drugs in the rural USA

Date Published: 2023-09-28

Abstract:
Despite high morbidity and mortality among people who use drugs (PWUD) in rural America, most research is conducted within urban areas. Our objective was to describe influencing factors, motivations, and barriers to research participation and retention among rural PWUD.

Introduction:
The rural United States (U.S.) is in the midst of an ongoing substance use disorder epidemic. In 2019, one in five Americans used an illicit drug and 70,630 drug overdose deaths occurred in the U.S, of which 71% were opioid-related [1, 2]. Further exacerbating the substance use epidemic is the prediction of the opioid epidemic’s “4th wave” or the rise in methamphetamine use among people with opioid use disorders [3,4,5,6]. People who use drugs (PWUD) such as opioids and methamphetamines face rising rates of HCV,…

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