why choose us

300×250 Ad Slot

Research Article: Hypocarnitinemia and its effect on seizure control in adult patients with intractable epilepsy on the modified Atkins diet

Date Published: 2024-01-05

Abstract:
Introduction: Previous studies have demonstrated the safety and efficacy of the modified Atkins diet (MAD) in attenuating seizures in patients with intractable epilepsy. MAD works by achieving ketosis, which is heavily dependent on the metabolic compound, carnitine, to facilitate the transport of long-chain fatty acids across the mitochondria for beta-oxidation. The effect of carnitine on ketogenic diet therapy is not well-defined in the current literature. Thus, the purpose of our study is to investigate the effects of hypocarnitinemia on the efficacy of MAD.

No summary available.

300×250 Ad Slot