Research Article: Functional Connectivity and Anxiety Improvement After Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease
Abstract:
Parkinson’s disease (PD) is a progressive degenerative neurological disease that occurs in elderly individuals and has a higher incidence in men than in women. Resting tremor, bradykinesia, and rigidity are the common motor symptoms of patients with most PD. In addition, a variety of non-motor symptoms (NMS), such as mood disorders, cognitive impairments, sleep disorders, and autonomic dysfunction, may be observed., Anxiety is one of the most common NMS of PD. Its prevalence among patients with PD is %, which is higher than that in patients with community or other diseases. It has shown to be a common worsening factor of the disease and is associated with a lower quality of life.– With the recent development of neuromodulation therapy, deep brain stimulation (DBS) has become an effective treatment for advanced PD., It is widely suggested that DBS can significantly improve anxiety and depression in patients with PD, but the mechanism remains unclear.,
Introduction:
Parkinson’s disease (PD) is a progressive degenerative neurological disease that occurs in elderly individuals and has a higher incidence in men than in women. Resting tremor, bradykinesia, and rigidity are the common motor symptoms of patients with most PD. In addition, a variety of non-motor symptoms (NMS), such as mood disorders, cognitive impairments, sleep disorders, and autonomic dysfunction, may be observed. , Anxiety is one of the most common NMS of PD. Its prevalence among patients with PD is %, which is…
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