Research Article: A Nomogram-Based Model for Predicting the Risk of Severe Acute Cholangitis Occurrence
Abstract:
Acute cholangitis is one of the common clinical abdominal conditions, which frequently presents an emergency, due to partial or complete biliary obstruction (by bile duct stones, malignant strictures, etc.), resulting in biliary stasis and biliary tract infection.– The Tokyo guidelines (TG) represent the current, globally accepted, criteria for diagnosis of acute cholangitis and for grading its severity. Patients are classified according to their clinical features and laboratory findings, at the time of admission into the hospital, as mild, moderate, and severe (grades I, II, and III) to determine their management. Once diagnosed, patients with severe acute cholangitis should be treated immediately with antibiotics and biliary drainage (Endoscopic retrograde cholangiopancreatography, ERCP). Several studies,, have demonstrated that -day mortality is significantly higher in patients with severe acute cholangitis compared with mild to moderate disease, but mortality can be significantly reduced in patients with severe acute cholangitis who receive early ERCP drainage.– Therefore, accurate assessment and prediction of the risk of severe acute cholangitis occurrence are crucial for early intervention and effective treatment.
Introduction:
Acute cholangitis is one of the common clinical abdominal conditions, which frequently presents an emergency, due to partial or complete biliary obstruction (by bile duct stones, malignant strictures, etc.), resulting in biliary stasis and biliary tract infection. – The Tokyo guidelines (TG) represent the current, globally accepted, criteria for diagnosis of acute cholangitis and for grading its severity. Patients are classified according to their clinical features and laboratory findings, at the time of admission…
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