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Research Article: Management of Suspected Life-Threatening Perioperative Anaphylaxis and Risk Factors for Near-Fatal and Fatal Outcomes: A Retrospective Study in China

Date Published: 2023-05-10

Introduction:
Life-threatening perioperative anaphylaxis (POA) is a severe, systemic hypersensitivity reaction that may lead to death during anesthesia. Clinical signs of life-threatening POA primarily affect the cardiovascular system (severe hypotension, tachycardia, or cardiac arrest) and respiratory system (bronchospasm, or increased airway pressure in ventilated patients); these symptoms may or may not be accompanied by skin changes. The reported incidence of POA varies between countries and ranges from one in , to one in…

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