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Research Article: Efficacy and Safety Study of Low-Molecular-Weight Heparin and Fondaparinux Sodium After Hip Arthroplasty: A Retrospective Cohort Study

Date Published: 2023-11-24

Abstract:
As the population lives longer, the number of patients with osteoarthritis increases, so does the number of patients treated with artificial joint replacement., Total hip arthroplasty (THA) is one of the most popular treatments for the hip. Total hip arthroplasty (THA) is currently an effective treatment for hip diseases. Deep vein thrombosis (DVT) is a disease of impaired venous return caused by abnormal clotting of blood in deep veins, which is a serious complication after total hip arthroplasty (THA), affecting the recovery of joint function and even threatening the recovery of joint function. DVT is a serious complication after total hip arthroplasty (THA), affecting the restoration of joint function and even threatening life It is a serious complication after total hip arthroplasty (THA). Relevant literature reports The incidence of DVT after THA can be as high as more than % if relevant preventive measures are not taken. Therefore, active and effective measures should be taken to reduce the incidence of DVT after THA to improve the prognosis of patients. Low molecular heparin (LMWH) and sodium pentoxifylline (FPX) are commonly used to prevent DVT after THA. However, data on the effects of both after TKA are still lacking. In this study, we compared the preventive effects of LMWH and FPX on lower extremity DVT after THA. Our findings may inform the selection of appropriate anticoagulation therapy after THA.

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