Research Article: Cryptotanshinone Reverses Corticosteroid Insensitivity by Inhibition of Phosphoinositide--Kinase-? in Chronic Obstructive Pulmonary Disease
Introduction:
COPD is a worldwide public health problem. Nowadays, COPD has become the third leading cause of death in the world. At present, there is no effective treatment to prevent the progress of COPD. Long-acting ? agonist (LABA) and long-acting muscarinic antagonist (LAMA) are the main treatment methods for stable COPD at present, which can relieve clinical symptoms, but will not significantly affect the potential disease progression. Inhalation of toxic gases and particles, including those in cigarette smoke, is a major…
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