Research Article: Decoding the Intercellular Cross-Talking Between Immune Cells and Renal Innate Cells in Diabetic Kidney Disease by Bioinformatics
Introduction:
The incidence of diabetes mellitus (DM) and its medical and social pressures have become a global burden and is expected to increase to % by . As one of the most serious microvascular complications of DM, diabetic kidney disease (DKD) remains as the most common cause of end-stage renal disease (ESRD) in developed world, notably in the elderly population. , Traditional renal injury hypothesis includes glomerular hyperperfusion, hyperpressure, and hyperfiltration. In addition, compensatory aggravation of renal…
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