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Research Article: Risk Factors for Cefoperazone/Sulbactam-Induced Coagulation Disorder

Date Published: 2023-09-21

Introduction:
Cefoperazone is a third-generation cephalosporin effective against intra-abdominal, urinary, and respiratory tract infections. Sulbactam is a ?-lactamase inhibitor that enhances cefoperazone activity. Cefoperazone/sulbactam can be used to treat moderate-to-severe infections caused by ESBL-positive Escherichia coli, Klebsiella pneumoniae , and other multidrug-resistant bacteria. , However, some studies have reported an association between cefoperazone/sulbactam and coagulation disorders. , Case reports have shown…

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