Research Article: Single-Cell RNA Sequencing Reveals Roles of Fibroblasts During Intestinal Injury and Repair in Rats with Severe Acute Pancreatitis
Introduction:
Acute pancreatitis (AP) is an unpredictable and potentially life-threatening disease, with prognoses largely dependent on the development of organ failure and infections. Despite advances in medical management and intensive care, the mortality rate of severe acute pancreatitis (SAP) is still very high. , SAP often results in multi-organ damage. The intestine is one of the most affected organs is SAP, and damage to the intestinal mucosal barrier can further exacerbate AP. The damage to the intestinal mucosal…
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