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Research Article: Neurofilament Light Chain in Aqueous Humor as a Marker of Neurodegeneration in Glaucoma

Date Published: 2023-08-02

Introduction:
Glaucoma is a neurodegenerative disease characterized by progressive loss of retinal ganglion cells (RGCs). It is a leading cause of irreversible blindness worldwide. Medical and surgical management of glaucoma currently center around controlling intraocular pressure (IOP), the only known modifiable risk factor. , Clinicians often use visual field testing and optical coherence tomography (OCT) to monitor RGC health and to guide treatment decisions. Nonetheless, these are surrogate endpoints that have limitations:…

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