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Research Article: Predisposing Factors for Granulomatous Lobular Mastitis: A Case-Control Study

Date Published: 2023-07-18

Abstract:
Granulomatous lobular mastitis (GLM), known as idiopathic granulomatous mastitis, was first reported by Kessler and Wolloch in . Epidemiological studies showed its incidence rate is .% in all breast diseases and varies by race. GLM usually uses pathological examination as the diagnostic criteria, which manifests multifocal non-caseous granulomas centered around the lobules. The morbidity of GLM in Hispanic and Asian women is higher than in other races. It usually occurs in the unilateral breast among women from to years old, and the incidence is high within five years after delivery. Early manifestations of the disease include a localized painful mass and redness of the breast, which would then develop into an abscess and ulceration and could form a sinus and fistula. GLM has a long course with easy relapses, seriously affecting the patients’ breast appearance and quality of life.

Introduction:
Granulomatous lobular mastitis (GLM), known as idiopathic granulomatous mastitis, was first reported by Kessler and Wolloch in . Epidemiological studies showed its incidence rate is .% in all breast diseases and varies by race. GLM usually uses pathological examination as the diagnostic criteria, which manifests multifocal non-caseous granulomas centered around the lobules. The morbidity of GLM in Hispanic and Asian women is higher than in other races. It usually occurs in the unilateral breast among women from to…

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