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Research Article: External Validation of the Nelson Equation for Kidney Function Decline in Patients with Acute Ischemic Stroke or Transient Ischemic Attack

Date Published: 2023-06-06

Abstract:
Accumulating evidence from clinical and basic studies indicated a tight interaction between the brain and the kidney. Kidney disease is an independent risk factor for the incidence of stroke and has adverse effects on stroke recurrence and disability., In addition, recent research demonstrated that the new-onset kidney injury after stroke leads to severe neurological deficits and poor functional outcomes.,, Given the potential for kidney disease prevention and management, the identification of stroke patients at an increased risk of declining kidney function serves to inform targeted risk factor modification and improve stroke prognosis.

Introduction:
Accumulating evidence from clinical and basic studies indicated a tight interaction between the brain and the kidney. Kidney disease is an independent risk factor for the incidence of stroke and has adverse effects on stroke recurrence and disability. , In addition, recent research demonstrated that the new-onset kidney injury after stroke leads to severe neurological deficits and poor functional outcomes. , , Given the potential for kidney disease prevention and management, the identification of stroke patients…

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