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Research Article: Risk Factors and Outcomes for Isolation with Polymyxin B-Resistant Enterobacterales from –: A Case-Control Study

Date Published: 2023-12-22

Introduction:
Multidrug-resistant Gram-negative bacilli have increased worldwide and pose a significant and growing threat that limits the effectiveness of therapeutic regimens. Conventional drugs, such as polymyxin E (colistin) and polymyxin B, are being reconsidered as the last line of defense against multidrug-resistant Gram-negative bacilli infections. Owing to the increased use of colistin in clinical settings, resistance to this antibiotic has increased, particularly among Klebsiella pneumoniae isolates, which should be…

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