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Research Article: Bikunin: A Promising Prognostic Biomarker for Acute-on-Chronic Liver Failure in Patients with Viral Hepatitis B

Date Published: 2023-08-31

Introduction:
Acute-on-chronic liver failure (ACLF) refers to a complex syndrome mainly manifested by acute jaundice and coagulation dysfunction caused by various triggers on the basis of chronic liver disease, which can be combined with complications such as hepatic encephalopathy, ascites, electrolyte imbalance, infection, hepatorenal syndrome, hepatopulmonary syndrome, and extrahepatic organ failure. – Hepatitis B virus (HBV) infection is a major etiology of ACLF. Due to the complex and diverse etiology, course and…

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