Research Article: The Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide ?g Administered by Inhalation as Single and Multiple (Twice Daily) Doses in Healthy Chinese Participants
Introduction:
Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation due to airway and/or alveolar abnormalities and is a leading cause of chronic morbidity and mortality worldwide. In China, the average prevalence of COPD is .% (ranging from .% to .% across different studies) with significantly higher rates among patients aged > years, underlining COPD as a major public health problem in this country. Studies in China have revealed tobacco exposure and biomass…
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