Research Article: Combined Therapy of Experimental Autoimmune Uveitis by a Dual-Drug Nanocomposite Formulation with Berberine and Dexamethasone
Introduction:
Uveitis, described as the intraocular inflammation of uveal tract (eg, iris, ciliary body, and choroid, etc.), is one of the leading causes of visual impairment among the working-age population. Generally, it can be classified into infectious and non-infectious uveitis, and noninfectious uveitis is related to systemic or idiopathic autoimmune conditions, known as autoimmune uveitis. The estimated prevalence of autoimmune uveitis is /, in the United States. Glucocorticoids (eg, dexamethasone (DEX)) remain the…
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