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Research Article: First Emergence of NDM- and OqxAB Efflux Pumps Among Multidrug-Resistant Klebsiella pneumoniae Isolated from Pediatric Patients in Assiut, Egypt

Date Published: 2023-09-08

Introduction:
Currently, there is increased awareness of the impact of Gram-negative bacteria that are resistant to carbapenem as it is the last choice treatment for bacterial infections. , Enterobacteriaceae exhibit resistance to carbapenems by three possible mechanisms: production of carbapenemase enzymes, efflux pump activity, and porin loss. , Carbapenemase production constitutes the basic mechanism of carbapenem resistance and study of this mechanism is essential for the best choice of recently effective antibiotics. ,

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