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Research Article: Lung Function and Asthma Clinical Control in N-ERD Patients, Three-Year Follow-Up in the Context of Real-World Evidence

Date Published: 2023-09-06

Introduction:
Nonsteroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD) is an entity characterized by hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs), nasal polyps, and asthma. It is considered an asthma phenotype with a very low frequency. The physiopathology is not yet clear, and the main hypothesis accepted is the blockage of the cyclooxygenase pathway by NSAIDs, increasing the synthesis of leukotrienes with subsequent induction of bronchospasm and nasal congestion after its intake. ,

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