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Research Article: Aptamer-Based Functionalized SERS Biosensor for Rapid and Ultrasensitive Detection of Gastric Cancer-Related Biomarkers

Date Published: 2023-12-11

Abstract:
Gastric cancer (GC) is one of the most common malignant tumors, with the second highest incidence and mortality rate of malignant tumors in the world., The -year survival rate of patients with early GC can reach %, while the -year survival rate of patients with advanced GC is only –%., One of the important reasons is that most GC patients do not have obvious symptoms in the early stage, so they miss the golden time of early diagnosis and are in the progressive stage when diagnosed.– Currently, the most reliable method to diagnose GC is endoscopy. However, endoscopy is an invasive test with certain risks and poor patient compliance and tolerance, so it is not suitable as a routine screening test.,

Introduction:
Gastric cancer (GC) is one of the most common malignant tumors, with the second highest incidence and mortality rate of malignant tumors in the world. , The -year survival rate of patients with early GC can reach %, while the -year survival rate of patients with advanced GC is only –%. , One of the important reasons is that most GC patients do not have obvious symptoms in the early stage, so they miss the golden time of early diagnosis and are in the progressive stage when diagnosed. – Currently, the most reliable…

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