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Research Article: RGS as a Biomarker of Pericytes, Involvement in Vascular Remodeling and Pulmonary Arterial Hypertension

Date Published: 2023-10-20

Introduction:
Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by a sustained rise in mean pulmonary artery pressure , due to increased pulmonary vascular resistance. PAH symptoms are nonspecific but usually include dyspnea and fatigue during exertion. If untreated, PAH typically progresses to progressive small vessel loss, lack of compensatory pulmonary angiogenesis, right ventricular hypertrophy and remodeling with outcomes of right ventricular failure and death (-year survival, %). The…

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