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Research Article: Surface-Modified Nano-Hydroxyapatite Uniformly Dispersed on High-Porous GelMA Scaffold Surfaces for Enhanced Osteochondral Regeneration

Date Published: 2023-10-21

Introduction:
Osteoarthritis (OA) is a prevalent age-related degenerative disease causing joint pain and cartilage breakdown, leading to a substantial economic impact. Current clinical treatment follows a stepwise approach based on disease stage and severity, aiming to improve outcomes, alleviate symptoms, and enhance patients’ quality of life. In cases of severe cartilage damage and bone marrow edema, patients may require reconstructive therapies, such as joint replacement surgery, which effectively alleviates pain but entails…

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