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Research Article: Pulmonary Tuberculosis and Rifampicin Resistant Mycobacterium Tuberculosis in Children and Adolescents using Gene Xpert MTB/RIF Assay in Tigray, Northern Ethiopia

Date Published: 2023-10-19

Abstract:
Tuberculosis (TB) is one of the leading causes of death worldwide. An estimated . million people fell ill with tuberculosis (TB) worldwide with . million children as reported in the World Health Organization fact sheet. Given the challenge in diagnosing childhood TB and perception, the burden of TB in children was higher than the estimate, indicating that childhood tuberculosis is a public health issue. Diagnosis of PTB in children is challenging because of nonspecific clinical or radiologic signs and the paucibacillary nature of the disease. To alleviate this diagnostic problem, the WHO recommended Xpert MTB/RIF assay in , a molecular method which is more sensitive and specific.

Introduction:
Tuberculosis (TB) is one of the leading causes of death worldwide. An estimated . million people fell ill with tuberculosis (TB) worldwide with . million children as reported in the World Health Organization fact sheet. Given the challenge in diagnosing childhood TB and perception, the burden of TB in children was higher than the estimate, indicating that childhood tuberculosis is a public health issue. Diagnosis of PTB in children is challenging because of nonspecific clinical or radiologic signs and the…

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