Research Article: Association Between Hypnotic Use and All-Cause Mortality in Patients with Chronic Obstructive Pulmonary Disease and Insomnia
Introduction:
Chronic obstructive lung disease (COPD) is a chronic debilitating disease characterized by progressive and often irreversible airflow limitation, chronic respiratory symptoms, and systemic manifestations caused by significant exposure to noxious particles or gases. It is the fifth leading cause of morbidity and mortality in the United States affecting millions of individuals. With a death toll expected to exceed million patients per year worldwide by , the economic burden of COPD on healthcare systems is enormous.
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