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Research Article: Increased Systemic Immune-Inflammation Index Was Associated with Type Diabetic Peripheral Neuropathy: A Cross-Sectional Study in the Chinese Population

Date Published: 2023-12-11

Abstract:
Diabetic peripheral neuropathy (DPN) is one of the most common long-term complications of diabetes that frequently presents with peripheral nerve dysfunction accompanied with typical characteristics of pain and numbness, which not only results in an increase in the risk of foot ulceration and subsequent amputation, but also leads to a considerable disability and cardiovascular mortality.– Therefore, DPN has posted a great challenge for both medical professionals and the entire society. Despite a high lifetime prevalence of approximately %, the symptoms are insidious in onset, and there is no approved therapy to prevent or cure DPN apart from good glycemic therapy. Therefore, emphasis should be laid on effective surveillance, early detection and diagnosis of DPN.

Introduction:
Diabetic peripheral neuropathy (DPN) is one of the most common long-term complications of diabetes that frequently presents with peripheral nerve dysfunction accompanied with typical characteristics of pain and numbness, which not only results in an increase in the risk of foot ulceration and subsequent amputation, but also leads to a considerable disability and cardiovascular mortality. – Therefore, DPN has posted a great challenge for both medical professionals and the entire society. Despite a high lifetime…

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