Research Article: Neonatal Cystitis Makes Adult Female Rat Urinary Bladders More Sensitive to Low Concentration Microbial Antigens
Introduction:
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic pain syndrome of unknown etiology. The clinical diagnostic criteria for this condition vary, with symptoms that may include severe urgency, frequency of urination, and pain involving the lower abdomen and perineal regions. The exact pathophysiology of IC/BPS is yet to be determined; however, the manifestation of this condition is likely a combination of inflammatory and neurophysiological pain factors (visceral and somatic) which are modified by…
Read more