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Research Article: Recommendations for the Implementation of the Self-Administration of Alpha- Antitrypsin

Date Published: 2023-08-04

Introduction:
Administration of exogenous alpha- antitrypsin (AAT) is the only specific therapy for the management of pulmonary morbidity in patients with AAT deficiency. , According to the Spanish registry on AAT deficiency, it is received by two-thirds of the patients with the genotype PI*ZZ, although large variations exist across Europe. Administration of exogenous AAT requires weekly or biweekly intravenous infusions, which may impact patient independence and quality of life. In a recent survey conducted among patients with…

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