Research Article: Usefulness of Serum Translocator Protein as a Potential Predictive Biochemical Marker of Three-Month Cognitive Impairment After Acute Intracerebral Hemorrhage: A Prospective Observational Cohort Study
Abstract:
Spontaneous intracerebral hemorrhage (ICH) is a frequently encountered emergency disorder that represents devastating cerebrovascular disease. Cognitive impairment has been believably accepted as a very common complication among ICH survivors and its emergence severely affects the quality of life among such patients. A series of molecular reactions such as inflammation, oxidation, apoptosis, and necrosis contribute to the pathophysiological processes underlying cognitive impairment. Conventionally, severity scales such as the National Institutes of Health Stroke Scale (NIHSS) and hematoma volume are used to predict cognitive impairment in patients with ICH. Notably, many researchers have gradually concentrated on various biomarkers that may aid in the prediction of cognitive impairment during clinical work of ICH.–
Introduction:
Spontaneous intracerebral hemorrhage (ICH) is a frequently encountered emergency disorder that represents devastating cerebrovascular disease. Cognitive impairment has been believably accepted as a very common complication among ICH survivors and its emergence severely affects the quality of life among such patients. A series of molecular reactions such as inflammation, oxidation, apoptosis, and necrosis contribute to the pathophysiological processes underlying cognitive impairment. Conventionally, severity scales…
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