why choose us

300×250 Ad Slot

Research Article: Prediction and Verification of Potential Therapeutic Targets for Non-Responders to Infliximab in Ulcerative Colitis

Date Published: 2023-05-15

Abstract:
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by continuous and diffuse inflammation of the colonic mucosa, which extends from the proximal rectum. As of now, the pathogenesis of UC is unclear, but risk factors include genetic susceptibility, environmental factors, autoimmunity, and gut microbiota., The high incidence of UC in developed countries and the substantial rise in the incidence in developing countries have made UC a global health issue.– A first-line drug for mild to moderate UC is -amino-salicylic acid (-ASA). Systemic corticosteroids are usually prescribed for moderate to severe UC. Corticosteroids should not be used for a prolonged period and only be used to induce remission. Several types of treatments are available to maintain remission, including azathioprine, anti-TNF, anti-integrins, and Janus kinase inhibitors.,

Introduction:
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by continuous and diffuse inflammation of the colonic mucosa, which extends from the proximal rectum. As of now, the pathogenesis of UC is unclear, but risk factors include genetic susceptibility, environmental factors, autoimmunity, and gut microbiota. , The high incidence of UC in developed countries and the substantial rise in the incidence in developing countries have made UC a global health issue. – A first-line drug for mild to…

Read more

300×250 Ad Slot