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Research Article: Autoimmune Disease-Related Hub Genes are Potential Biomarkers and Associated with Immune Microenvironment in Endometriosis

Date Published: 2023-07-10

Abstract:
Endometriosis (EMT) is a disease in which endometrium-like tissue grows outside the endometrium. EMT is an inflammatory endometrial disease that affects women of reproductive age and is progesterone and oestrogen dependent. Approximately million women and teens globally are affected by it, or between and % of women of reproductive age., The staging of endometriosis is based on the location, number, size and degree of adhesions of the ectopic endometrium, but the severity of symptoms or recurrence of endometriosis is not related to stage. For example, women with revised American Society of Reproductive Medicine (rASRM) stage I disease may have severe pain, infertility, or both, whereas stage IV endometriosis may be asymptomatic. When symptoms of EMT are severe, it can cause recurrent dysmenorrhoea, persistent pelvic pain, abnormal menstruation and non-uterine amenorrhoea, leading to infertility in women. According to some reports, EMT affects % to % of women who experience chronic pelvic pain.

Introduction:
Endometriosis (EMT) is a disease in which endometrium-like tissue grows outside the endometrium. EMT is an inflammatory endometrial disease that affects women of reproductive age and is progesterone and oestrogen dependent. Approximately million women and teens globally are affected by it, or between and % of women of reproductive age. , The staging of endometriosis is based on the location, number, size and degree of adhesions of the ectopic endometrium, but the severity of symptoms or recurrence of endometriosis…

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