Research Article: IDO Promotes the Progression of NSCLC by Regulating the Polarization of M Macrophages
Introduction:
Lung cancer is the leading cause of cancer-related death in men and women worldwide. Non-small cell lung cancer (NSCLC) accounts for ~% of all lung cancer cases. NSCLC is a tumor with poor chemotherapy sensitivity, which is only applicable to about % of patients with EGFR, ALK, and ROS mutations and can be targeted for treatment. Accordingly, NSCLC, which has a high risk of progression and recurrence, requires neoadjuvant treatment. Despite the reported success of immune checkpoint inhibitors in treating various…
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