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Research Article: Perioperative Administration of Pregabalin and Esketamine to Prevent Chronic Pain After Breast Cancer Surgery: A Randomized Controlled Trial

Date Published: 2023-06-08

Abstract:
Breast cancer is one of the most important health concerns for women worldwide, accounting for approximately % of cancer cases in China and increasing gradually in prevalence. Breast cancer management differs depending on the cancer type, but surgery remains the main treatment. Chronic postsurgical pain is a common complication that significantly affects patients’ quality of life and is closely related to mortality. A large-scale cross-sectional study reported that % of the patients had chronic pain after breast cancer surgery, % with moderate pain, and % with severe pain. Therefore, it is important to prevent the development of chronic pain after breast cancer surgery.

Introduction:
Breast cancer is one of the most important health concerns for women worldwide, accounting for approximately % of cancer cases in China and increasing gradually in prevalence. Breast cancer management differs depending on the cancer type, but surgery remains the main treatment. Chronic postsurgical pain is a common complication that significantly affects patients’ quality of life and is closely related to mortality. A large-scale cross-sectional study reported that % of the patients had chronic pain after breast…

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