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Research Article: DNA Methylation Changes in Blood Cells of Fibromyalgia and Chronic Fatigue Syndrome Patients

Date Published: 2023-11-30

Introduction:
Fibromyalgia (FM) and Chronic Fatigue Syndrome (CFS) are characterized by chronic pain, fatigue, and weakness. Patients with these symptoms also suffer from sleep abnormalities and report affected cognitive processes such as memory. The diagnosis of these two syndromes is challenging and is based on questionnaires that make the diagnosis rather difficult and prone to be subjective. Currently, the American College of Rheumatology (ACR) criteria are the most widely used in the diagnosis of FM – and for CFS diagnosis…

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