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Research Article: Efficacy of Nirmatrelvir-Ritonavir versus Azvudine for COVID- Treatment in Tibet: A Retrospective Study

Date Published: 2023-09-11

Abstract:
Globally, coronavirus disease (COVID-) continues to cause public health concerns, resulting in millions of deaths. The spread of COVID- has not yet been completely controlled. From June to July , overnew cases and over deaths were still reported worldly. With the emergence of novel and evolving SARS-CoV- variants, new vaccines and drugs are needed. Nirmatrelvir-ritonavir was granted Emergency Use Authorization for COVID- patients in December to fight the disease. Currently, many studies have indicated nirmatrelvir-ritonavir could reduce the risk of disease progression to severe COVID-, the viral clearance time, and the length of hospitalization., Nevertheless, a few practical points still need to be noted regarding real world application of this drug. Despite being given as a short treatment course, drug?drug interactions cause the most concern. Moreover, $ for a -day session may not be affordable for all patients. Consequently, the development of novel small molecule antiviral drugs is urgently required.

Introduction:
Globally, coronavirus disease (COVID-) continues to cause public health concerns, resulting in millions of deaths. The spread of COVID- has not yet been completely controlled. From June to July , overnew cases and over deaths were still reported worldly. With the emergence of novel and evolving SARS-CoV- variants, new vaccines and drugs are needed. Nirmatrelvir-ritonavir was granted Emergency Use Authorization for COVID- patients in December to fight the disease. Currently, many studies have indicated…

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